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Breast Cancer

In 2013, breast cancer affected more than 230,000 women and 2,300 men. That year, it claimed the lives of nearly 40,000, making it the second most deadly cancer for women. As a National Cancer Institute-designated Cancer Center, CSHL is a leader in breast cancer research, working to understand the biology of cancer and develop new diagnostics and therapies.


The Laboratory employs a multidisciplinary approach to identify new proteins and biological processes that are critical for breast cancer development.  These pathways become the targets for cutting-edge drugs and treatments to halt breast cancer progression. At the same time, CSHL scientists are applying advanced technologies to better understand the progression of the disease for earlier detection and prevention.

New targets, new treatments
A significant portion of breast cancer research at CSHL is dedicated to identifying new drug targets and therapies.  From innovative imaging techniques to RNAi-based searches to the latest in DNA sequencing technology, CSHL scientists are leading the fight against breast cancer.

Prevention & diagnosis
CSHL scientists are looking for more than a cure. They are using the latest technology in the search for methods to detect breast cancer earlier or even prevent it altogether.


Abnormal process of protein production in cells can spur tumors  10/1/2015

Mammary glands remember previous pregnancy with implications for breast cancer  5/7/2015

Tumor cells can mimic blood vessels and spread outside the breast  5/8/2015

Enzymes play a role in breast cancer and treatment  4/20/2015

See live tumor cells and normal cells interact

Live imaging shows how to boost cancer drug impact  4/16/2012


Mikala Egeblad

Camila dos Santos

Jim Hicks

Gregory Hannon

Adrian Krainer

Alexander Krasnitz

David Spector

Bruce Stillman

Nicholas Tonks

Michael Wigler


Science Shorts: Attacking Cancer in Living Color - Mikala Egeblad, Ph.D. 6/6/2015

Seeking out cancer: From early detection to treatment - Michael Wigler, Ph.D. 6/17/2015

Evelyn Lauder receives Double Helix Medal

Single-cell sequencing to diagnose cancer

Dr. Mary-Claire King awarded the Double Helix Medal